In DIC, what is a consequence of clotting factor depletion?

In DIC, what is a consequence of clotting factor depletion?

• A. Increased risk of hemorrhage
• B. Decreased bleeding risk
• C. Hypertension
• D. Hypercoagulability

Answer: (A)

Clotting factor depletion in DIC happens because widespread activation of coagulation uses up clotting factors and platelets faster than the body can replace them. This consumption coagulopathy means the blood’s ability to form clots becomes impaired, so bleeding becomes more likely. That’s why the key consequence is an increased risk of hemorrhage, even as there may also be initial clot formation. The other options don’t fit: depletion does not cause decreased bleeding risk or hypertension, and while DIC can involve a tendency to clot early, the net effect after factors are used up is more bleeding than hypercoagulability.

Clotting factor depletion in DIC happens because widespread activation of coagulation uses up clotting factors and platelets faster than the body can replace them. This consumption coagulopathy means the blood’s ability to form clots becomes impaired, so bleeding becomes more likely. That’s why the key consequence is an increased risk of hemorrhage, even as there may also be initial clot formation. The other options don’t fit: depletion does not cause decreased bleeding risk or hypertension, and while DIC can involve a tendency to clot early, the net effect after factors are used up is more bleeding than hypercoagulability.