Which statement is a transplantation option used in non-Hodgkin's lymphoma management?

Which statement is a transplantation option used in non-Hodgkin's lymphoma management?

• A. Bone marrow transplantation
• B. Pharmacologic sedation
• C. Splenectomy
• D. Vitamin supplementation

Answer: (A)

Transplantation in non-Hodgkin lymphoma focuses on replacing the diseased hematopoietic system with healthy cells to allow high-dose chemotherapy and to eradicate lymphoma cells. Bone marrow transplantation, now more commonly called hematopoietic stem cell transplantation, can be autologous (using the patient’s own cells) or allogeneic (donor cells). This approach can enable higher-dose treatment and may produce a graft-versus-lymphoma effect, offering a potential benefit in relapsed or high-risk cases. Other options such as pharmacologic sedation, splenectomy, or vitamin supplementation do not constitute transplantation and serve different roles (symptom control, surgical management, or nutritional support).

Transplantation in non-Hodgkin lymphoma focuses on replacing the diseased hematopoietic system with healthy cells to allow high-dose chemotherapy and to eradicate lymphoma cells. Bone marrow transplantation, now more commonly called hematopoietic stem cell transplantation, can be autologous (using the patient’s own cells) or allogeneic (donor cells). This approach can enable higher-dose treatment and may produce a graft-versus-lymphoma effect, offering a potential benefit in relapsed or high-risk cases. Other options such as pharmacologic sedation, splenectomy, or vitamin supplementation do not constitute transplantation and serve different roles (symptom control, surgical management, or nutritional support).